Comparative Study of Monopolar and Bipolar Transurethral Resection in Patients with Benign Prostatic Adenoma Omar S. Salih*, Entidhar J. Al-akkam This study included eight adult patients with AIDS and chronic diarrhea diagnosed stool cystosisporiasis (oocysts) and / or duodenal biopsies (asexual and sexual stages in epithelium). There was no significant difference in intra-operative mean serum sodium, potassium, chloride, and creatinine between both groups (p > 0.05). Frequency of OGG1 C/C (homozygous) genotype showed (32.43%) in patients and (100%) in control. View and Download Full Article This International Council for Harmonisation (ICH) Q12 guideline intends to enhance the supervision of the post-approval chemistry, manufacturing, and control changes most reliably and effectively both for pharmaceutical industries and regulatory authorities. The Antioxidant and DNA Protection Activity of the Tarragons Methanolic Extract Objective: This work involves the preparation and in vitro characterization of a topical gel formulation that is capable of deep skin permeation, providing the anti-inflammatory effect for the optimum nano ethosomal dispersion formula. The total calcium and serum ALK were measured by spectrophotometric-based method. Abstract The results of OGG1 heterozygous G/C genotype showed higher significantly in DM type1 (74.76%) and not found in controls (0.00%). The study population comprised 60 T1DM patients of both genders, 38 females and 22 males. In this review article, we discuss the benefits and challenges related to this enhanced framework. Long-term use may cause many side effects, such as white water on the eyes, brittleness, weak bones, and stomach ulcers and an increase in blood sugar (glucose) and growth retardation for children. Methods: Two hundred and fifty samples were collected from various sites in Baghdad, Iraq hospitals and divided into two groups based on their source: clinical 150 and environmental (100) samples, collected from October 2020 to March 2021. It is noted that the rate of reaction increases with increasing the palladium ion concentration. This demonstrated that both extracts are harmless when taken orally. Genotyping of the gene LPL Ser447Ter polymorphisms rs328 was performed using polymerase chain reaction (PCR)- allele-specific primers. the lowest rate of breast cancer females was found within the age groups 2029 years (2.5%), and highest rate in age group 50 to 59 years (32.5%). A biochemical test was performed to determine the concentration of random blood sugar (RBS). Elaf M. M. Raoof, Hind S. Ahmed* The new ICH Q12 guideline Technical and regulatory considerations for pharmaceutical product lifecycle management assist the management of post-approval chemistry, manufacturing, and controls (CMC) changes in an effective way with regard to the pharmaceutical companies. The study comprised 35 women between 18 and 35 who had PCOS based upon complete Rotterdam criteria. The natural fibers structure consists of (cellulose, hemicelluloses, lignin, pectin, and waxy substances) and permits moisture absorption from the surroundings which causes weak bindings between the fiber and polymer. View and Download Full Article You are accessing a machine-readable page. Alaa A. H. K. Al-Daamy* Four ethosomal gel formulas (G1-G4) were prepared by using carbopol 934 and carbopol 940 at 1% and 1.5% concentration at a 1:1 ratio as a gelling agent. On day 15, whole blood was collected in clean ethylenediaminetetraacetic acid (EDTA)-vacutainer. Chemoprevention of photocarcinogenesis by selected dietary botanicals. Zinc, an essential dietary metallic, shows different parts in the leading routes and partially underwrites numerous organic enzymes construction and purpose. Methods: A total of 200 children aged 112 years enrolled in this case-control study. Suaad T. Zamil, Suhad T. Zamil, Naser A. Naser*, Hussein A. Kadhim Moringa oleifera Lam. And that most patients are aged, particularly men. Methods: C. olitorius leaves extracted with 60% methanol then phytochemical analysis done, forty male rats separated into four groups ten in each the first not received any treatment as a normal control, remaining rats were induced diabetes type 2 by 28 days feeding of high fat diet followed by single intraperitoneal injection of streptozotocin 35 mg/kg, ten of them not received treatment served as diabetics, third and fourth groups received oral metformin (MET) 100 mg/kg and C. olitorius methanol extract (COME) 400 mg/kg respectively for 28 days. Analysis Polymorphism of DNA Repair Gene (OGG1) in some Kirkuk Patients with Type 1 Diabetes Mellitus Those patients showed signs of IR. View and Download Full Article View and Download Full Article The mean of IL-6 pg/mL with body mass index, shown overweight recorded (6.797 pg/mL). The identification of 83 isolates was verified using a molecular approach based on the rplB gene, an essential gene found in this genus. View and Download Full Article Synthesis and Identification of some New N-Topylated Ligand Complexes with some Metalic Ions Co(II), Ni(II), Cu(II) and Zn(II) Evaluation Fitness of Alcoholic Extract of Laurus nobilis Leaves on Lipid Profile and some Physiological Parameters in Female Albino Rats Treated with Depakin Drug However, some cases show no significant variation. View and Download Full Article Only a few researchers have looked at the link between age and the occurrence of polycystic ovary syndrome (PCOS). The age range of patients was between 18 and 94 years, with 45 males and 55 females. The hemolytic activity process was applied to erythrocytes by an analyst, as well as the lysis of erythrocytes resulted in a positive test result. Mylanta, omeprazole, and sustained released baclofen, domperidone, omeprazole, esomeprazole, and rebamipide are more effective and have been used recently in combination for treating GERD patients. Synthesis and Identification of some New N-Topylated Ligand Complexes with some Metalic Ions Co(II), Ni(II), Cu(II) and Zn(II) 42. This study included eight adult patients with AIDS and chronic diarrhea diagnosed stool cystosisporiasis (oocysts) and / or duodenal biopsies (asexual and sexual stages in epithelium). Regarded aqueous plant extracts the maximum inhibition zone was observed in 50% concentration Clove (28 mm) and Ginger (25 mm). Shaymaa M. Hisham, Adnan M. Mohammad, Muthanna J. Mohammed* These samples include 52 isolates of P. aeruginosa, which consider the aims of this study at a rate of (15.07%) from the total number of samples (345). Vitamin D and its Relationship with Female Outfit Dressing Style Treatment with MET or COME significantly reduced the elevated levels of fasting blood glucose, glycated hemoglobin A1, homeostasis model assessment of insulin resistance, total cholesterol, triglycerides, low density lipoprotein and very low density lipoprotein, while, enhance the reduced levels of adiponectin and high density lipoprotein, also COME enhanced insulin release. The therapeutic efficiency in reducing the degree of redness and sensitivity was 60% compared to 56% in the commercial formula, as well as the clinical safety parameters are better from its comparison of general results, there is a significant increase in absorptivity, efficacy, safety, and consistency of the formula Noder compared to the commercial formula. Age and sex-matched children. there were significant differences in body mass index (BMI) (p 0.01) in control group when matching with found in controls (0.00%). Conclusions: EPO and DIF are ineffective as anticancer drugs; EPO and DIF are toxic to the normal cells and nonselective in their action toward cancer cells. In addition, there was no significant difference in the rate of repetition of TURP between the monopolar group and plasma edge group, 1 (1.7%) versus 1 (1.7%), respectively (p = 1.000). Besides, microorganisms like cyanobacteria and actinomycetes are also known for the degradation of lignin; however, the level of degradation varies with microorganisms. Mean Hb level was significantly lower in the monopolar group compared to the plasma edge group, 14.00 1.64 g/dL versus 15.03 1.26 g/dL, respectively (p < 0.001). Manar G. Sabbagha, Zayd K. Omer, Alyaa F. Al-Omari* Results: Eighty-three A. baumannii isolates were identified by microscopic examination and biochemical tests. Mean IPSS was significantly lower in the monopolar group compared to the plasma edge group, 26.18 4.12 versus 28.05 4.09, respectively (p = 0.014). 71. Abstract That means there is no direct damaging effect of edible tarragon leaves on the human genomic DNA, which may be strongly related to the content of active phytochemicals (tannin and flavonoids) in leaves. Both flavonoid and tannin were found in Tarragons methanolic extract with about13.4 0.133 mg of quercetin equivalent/gm of flavonoid and 17.7 2.05 mg of tannic acid equivalent/gm of tannin. The normal control group (n=8) received intramuscular normal saline twice weekly (the vehicle of dexamethasone) and subcutaneous normal saline daily (the vehicle of liraglutide); the negative control group received intramuscular dexamethasone 2.5 mg twice weekly and subcutaneous normal saline (vehicle of liraglutide); liraglutide treatment group received intramuscular normal saline twice-weekly (vehicle of dexamethasone) and subcutaneous liraglutide 75 g/mL daily. Relation between Acetyl-CoA Carboxylase with some Biochemical Variables in Iraqi Men with Acute Myocardial Infarction and Diabetes Infection with Cystoisospora belli causes severe diarrhea, bile duct involvement, and Extra-intestinal spread in patients with acquired immunodeficiency syndrome (AIDS). In conclusion, P. khinjuk possesses immunomodulatory and antioxidant properties against the adverse effects of cyclosporine in rats. This implies that while infected with H. pylori, the concentration of free T4 was unaffected. Abstract Mylanta, omeprazole, and sustained released baclofen, domperidone, omeprazole, esomeprazole, and rebamipide are more effective and have been used recently in combination for treating GERD patients. Conclusion: There was a clear link between the presence of the bap gene and the prevalence of multidrug-resistant isolates. Pyridoxine is the usual form of vitamin B6 included in pharmaceutical products. The Antioxidant and DNA Protection Activity of the Tarragons Methanolic Extract Laboratory investigation results were retrieved from patients records and included random blood sugar, lactate dehydrogenase, d-dimer, HbA1c%, and C-reactive protein (CRP).Results: The mean values of age, random blood sugar (RBS), lactate dehydrogenase (LDH), d-dimer, HbA1c, and HS-CRP were comparable between males and females (p > 0.05). Vit D had a constant function in adaptive and inherent immunity. Almost the Tarragons section has a protective and no damaging effect on DNA. Bioeng., 22: 65-77. Khushbu Jain*, Neetesh K. Jain The random sample method and the statistical analysis of the results were adopted, the results showed that the acne free formula had the ideal physical properties as in Table 1 and the absorption is higher than the commercial formula and has stability for a period about 36 months. Objectives: Dental caries is an oral illness caused by Streptococcus mutans formation biofilms, which playing an important role in the formation of virulent cariogenic biofilms. Conclusion: There was a clear link between the presence of the bap gene and the prevalence of multidrug-resistant isolates. Adsorption is often applied to surfaces with pores; widely available industrial wastage produced Antimony trioxide Sb2O3, is chosen such as an adsorbent to Murexide dye. A prospective controlled study at Al-Diwaniya Urological center was compared two procedures (M-TURP and B-TURP-PLASMA ADGE). Shahad A. Abdulkareem, Susan J. Ali*, Dlnya A. Mohamad Eman H. Sahap*, Fatima A. There are only 35 isolates that test positive for these genes. At the same time, there were immunostimulatory effects in groups treated with extract Group 4, 5, 6, and 7, with a significant increase (p > 0.05) in the total number of WBC, Differential count and antibody concentration, and Cytokine level (TNF-, CCL5, NF-B). This study is designed to examine the effect of pyridoxine in two different doses, each co-administered with methotrexate at 20 mg/kg made renal toxicity in rats through the involvement of Nrf2/HO-1 molecular mechanism in this respect. Noor H. Swayeh*, Haitham M. Kadhim The immunostimulatory effect of the methanol extract of Pistacia Shinjuku was tested in male rats. Comparative Study of Monopolar and Bipolar Transurethral Resection in Patients with Benign Prostatic Adenoma All concentrations of DIF and EPO (except the concentration of 1000 g/mL of EPO) show significant (p < 0.01) higher growth rate inhibition in the vero cell line in comparison to the HCT 116 cell line. Results and Conclusions: Results showed a significant increase in levels of ACC, cTnT, CRP, Glucose, and Lipid profile except for high-density lipoprotein cholesterol (HDL-C) and urea, while a significant decrease with Na and K also a non-significant variation was observed with Cl and creatinine in AMI and diabetes patients compared to control group. It causes a variety of symptoms, including urgency, incontinence, urine frequency, and nocturia. One long-term complication is the ischemic heart disease (IHD) which is a major cause of morbidity and mortality. Abstract Pavithra G.M., Nagalakshmi S.* Baldrian, P. Fungal LaccasesOccurrence and Properties. Abstract View and Download Full Article Jamal A. Ashoor*, Mowafaq M. Ghareeb Assess serum glucose, insulin levels, and HOMA-IR in T2D patients and IHD and compare them with healthy individuals. Shabaraya A. R, Sumana G*, K Vineetha Abstract The solvent/anti-solvent precipitation method was used to make darifenacine nanoparticles. Abstract Wijdan B. Abid*, Hanan R. D. Hussain, Dalia H. Al-Hamawandy Measurement of IL17A, FGF21 and CXC12 levels were performed by ELISA. ; data curation, Q.Y. It has a higher selectivity for the bladders muscarinic receptors. The rate of active substance absorption was 8% compared to 5% in the commercial formula. The study aims to increase the absorption, efficacy, and stability of topical treatment through the combination of nano crystalline crystals of spironolactone-ofloxacin-clindamycin-ascorbic acid and then test the resulting compound by diagnosing physical-chemical properties and measuring the absorptivity of the formula across the skin as well as measuring response and clinical safety. So, the aim of the present review is to provide comprehensive information from recognized sources on the ethnobotany, traditional uses, phytochemistry and pharmacological efficacy and of the medicinal plant, M. oleifera. Abstract Abstract Nanoparticles are produced using appropriate techniques for drug delivery applications and administered via various routes, including oral, topical, parenteral, ophthalmic, and pulmonary. Female: male ratio is almost 1:1 in the three studied groups. 15521596, 2012. Antibiotic susceptibility testing was performed on all 83 identified isolates, and the findings revealed that 36 isolates had MDR. The findings of the immunohistochemical study showed the same concentrations for both liver and muscle samples using CD marker of TNF-; in the liver, at the concentration (492 ppb), there was strong immune expression (+++), while the immune expression was (++) at the concentration (467 ppb), and no expression (-) was detected at the concentration (65 ppb). This study demonstrated the role of rplB gene for molecular detection A. baumannii at the level of genus and species, respectively. Antibacterial agents are used to treat a wide range of infections, cancer, protozoa, and helminths. The results of the aflatoxin B1 detection showed that all samples were contaminated with this toxin at different concentrations ranging from 25422 ppb and 65492 ppb for each ulna muscles and liver, respectively. Studies found that both hormones participate in the development of T2DM and IHD, beside their role in the pathophysiology of metabolic syndrome. Synthesis and Evaluating the Antimicrobial Activities of Various Adducts Prepared from Isatins and Proline El resveratrol en su formulacin patentada SRT-501 (3 o 5 g), desarrollada por Sirtris Pharmaceuticals, alcanz niveles en sangre cinco a ocho veces mayores. Esraah Alharris*, Dina Saleh View and Download Full Article Wathiq A. Al-Draghi, Sajjad A. Wahab*, Shahad T. Hamad Mohammed Q. Sultan*, Husam M. Kredy, Bassem Charfeddine Abstract Group 4 (G4) (methanol extract of P. khinjuk, 3 g/kg/body weight) for 14 days, Group 5 (G5): methanol extract of P. khinjuk, 1.5 g/kg/body weight) for 14 days. [34] La capacidad directa del resveratrol de activar SIRT1 ha sido puesta en cuestin,[35][36][37] aunque muchos nuevos intentos tratan de volver a confirmar este vnculo,[38] una investigacin ms reciente ha demostrado que el resveratrol se una a TyrRS para potenciar una sealizacin en cascada de PARP1/NAD+ y a su vez activar p53 y AMPK por medio de la inhibicin de SIRT1. The brain is wide and short and its length 1.5 cm, and it consists of three regions. The results show no significant variations in free T4 concentrations between males and females for both positive and negative tests (p > 0.05). Abstract The immunostimulatory effect of the methanol extract of Pistacia Shinjuku was tested in male rats. Pages 11-22. https://doi.org/10.1016/0141-0229(80)90003-4. Abstract It is the third-largest method of medication delivery, after only intravenous administration and oral administration. The ethanolic extract of Laurus nobilis leaves possesses loss of weight and hypolipidemia. Your information is safe with us. This work expresses the construction of dye-sensitized solar cells (DSSCs) from TiO2 thin films with complex Ni-azo dye and azo ligand. View and Download Full Article The levels of Interleukin 1 beta (IL-1) pg/mL were (5.04 pg/mL) in (>60) years and 2.87 pg/mL in age 2029 yrs., with significant differences. 45. 72. They were compared with 30 healthy subjects as control group. Alaa A. Nayif, Muneer A. Al-Da,amy, Salih H. Kadhim* The biological activity of the prepared derivatives was studied on two types of bacteria that cause urinary tract and measuring the diameter of the inhibition zone against the growth of these bacteria. Abstract BMI, FBS, serum insulin, HOMA-IR, and fetuin-A were measured or calculated for each participant. Formulation and Evaluation of Topical Formula Gel for Dermatitis and Inflammations In contrast, 4-hydroxy benzoic acid and coumarin had a killing rate of 90% at a concentration of 20%. The cleavage of the -O-4 ether bond is considered an important step for lignin depolymerization as it represents about 50% of all linkage sin lignin. The formation of biofilm has founded a vary from strong to weak. View and Download Full Article In addition, there was no significant difference in the rate of repetition of TURP between the monopolar group and plasma edge group, 1 (1.7%) versus 1 (1.7%), respectively (p = 1.000). Ilaprazole, and tenatoprazole are currently under trial in humans and reported to have a longer duration of action. View and Download Full Article Skin allergy is a widespread skin problem at the level of different ages, and it occurs when an irritant comes into contact with the skin, and immune system believes it is under attack, so it overreacts and sends antibodies to help fight invaders. View and Download Full Article A quantitative test was used to determine 25-hydroxy Vit D in human serum using minividase and for total calcium measurement atomic absorption spectrophotometry. In chemotherapy, diagnostics, treatment, and immunotherapy, microneedles were utilized. Methotrexate is an anti-metabolite used in low doses for autoimmune and inflammatory disorders and high doses for different malignancies. Combinations therapy is more effective than monotherapy and also decreases therapeutic challenges which arise by using monotherapy of these drugs in GERD patients. The laboratory study included diagnosing the physical and chemical properties of the formula by means of optical spectroscopy, pH measurement, peroxide, viscosity, and image processor technology in comparison to the traditional formula. Incorporation of Nickel with Azo Dye and its Applications in Dye-Sensitized Solar Cells Synthesis and Identification of some New N-Topylated Ligand Complexes with some Metalic Ions Co(II), Ni(II), Cu(II) and Zn(II) View and Download Full Article View and Download Full Article This International Council for Harmonisation (ICH) Q12 guideline intends to enhance the supervision of the post-approval chemistry, manufacturing, and control changes most reliably and effectively both for pharmaceutical industries and regulatory authorities. The results showed that the Schiff bases compounds illustrated weak effectiveness against S. aureus. Facile Synthesis and Antioxidant Activity of Pyrimidine Derivatives via Thienyl Chalcones Under Phase Transfer Catalysis Method These samples include 52 isolates of P. aeruginosa, which consider the aims of this study at a rate of (15.07%) from the total number of samples (345). It suffers from extensive first-pass metabolism with a short elimination half-life and ranging between three to four hours). This study implements a consensus about the Iraqi O. ecklonis plant as a promising plant for its different secondary metabolites, especially the phenolic acids, which detected novelty in this study. This implies that while infected with H. pylori, the concentration of free T4 was unaffected. The formation of biofilm has founded a vary from strong to weak. 79. Several materials, such as metals, inorganic, and polymer materials, are used to create microneedles. View and Download Full Article Several materials, such as metals, inorganic, and polymer materials, are used to create microneedles. Its (ML13ph) mixed ligand complexes [M= Co (II), Ni (II), Cu (II), Zn (II), and Cd (II); (H1L1) = -enaminone ligand=L1 and (3ph) =3-aminophenol= L2]. 51. The MDA level significantly increases (p 0.01) in G1 compared with a control group. The mechanism of reaction of the synthetic compounds and their structures were established using physical analysis methods 1H-NMR and IR. Prior to synthesis, an in silico computational analysis was conducted to determine the binding interactions of these synthesized compounds in the active sites of the fungal enzyme sterol 14-demethylase (CYP51) through molecular docking via Genetic Optimization for Ligand Docking (GOLD) suite v.5.6.2. After intravenous and immediate-release oral dose forms. Effects of Co-administration of Pyridoxine in Two Different Doses with Methotrexate-induced Nephrotoxicity in Rats Maximum flow rate (Q max) was significantly more in the monopolar group in comparison to the plasma edge group, 16.62 1.89 versus 15.03 2.20, respectively (p < 0.001). Risperidone chemically name is 3-[2-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-1- piperidinyl] ethyl]-6, 7, 8, 9-tetrahydro- 2-methyl-4H-pyrido [1, 2-a] pyrimidine-4-one. It also controls ion trailers applicable to pulmonary illnesses. Esraah Alharris*, Dina Saleh Group 7 (G7): methanol extract of P. khinjuk 1.5 g/kg/body weight) for 14 days after cyclosporine injection. 72. The sensitivity of P. aeruginosa before irradiation to a number of antibiotics gives high resistance to the antibiotics used in this study. The administration of BPA (450 mg/kg) begins from the seventh to the eighteenth day of pregnancy. View and Download Full Article View and Download Full Article The immunostimulatory effect of the methanol extract of Pistacia Shinjuku was tested in male rats. Methods: This study was performed on 24 grown-up Wistar pale-skinned adult rats. Finally, a mechanism for the oxidation reaction is suggested in this work. Shahad A. Abdulkareem, Susan J. Ali*, Dlnya A. Mohamad From the SEM analysis it was found that nanosponges are spherical, discrete with smooth surface. 54. View and Download Full Article The disorder of lipid metabolism is one of the characteristics of diabetes, which is considered a risk factor for MI. 77. The study started on Sept 15, 2021 and ended on Apr 15, 2022. Noor M. Jasim*, Entesar J. Fadhil The spectroscopic studies (Fourier-transform infrared spectroscopy (FTIR), UV-vis, and Proton Nuclear Magnetic Resonance (1H-NMR)) are used to identify the azo ligand and its complex Ni (II) to synthesize the DSSCS. Analytical and spectroscopic techniques like chloride content, micro-analysis, magnetic susceptibility UV-visible, conductance, and FTIR spectra were used to identify mixed ligand complexes. After 72 hours of treatment with various concentrations of terpenoids saponins extracts (25, 50, and 100 mg/kg BW), no mortality was detected in the rats of the trials. Microneedles as A Magical Technology to facilitate Transdermal Drug Delivery: A Review Article The hemolytic activity process was applied to erythrocytes by an analyst, as well as the lysis of erythrocytes resulted in a positive test result. The study was cross-sectional and included 100 patients with a diagnosis of COVID-19 evidenced by polymerase chain reaction (PCR) test and CT-scan computed tomography scan of the chest. The needle comes into contact with the epidermal layer of the skin before it gets to the dermal layer, where there is no discomfort. 80. These samples include 52 isolates of P. aeruginosa, which consider the aims of this study at a rate of (15.07%) from the total number of samples (345). Effect of Azithromycin on Sperm DNA of Male Rats The histopathological and immunological study was conducted in meat samples containing higher and lower concentrations of the toxin. Evaluation of the Cytotoxic Effect of the Epoxyconazole and Difenoconazole on Human Colorectal Cancer HCT116 Cell Line Abstract Lifestyle is a part of life that is actually being realized and encompasses a full range of activities that people do in daily life. 32. Abstract Study of Histological Structure of Mesencephalon in White Cheeked Bulbul (Pycnonotus leucotis) Following Cholecystectomy (after 4 weeks), in some cases, changes occur in liver function tests where the finding of ALT, AST, and ALK-P closely shows restoration to normal. Clinical trials using Moringa for a variety of combinations in different formulations should also be conducted. The newly prepared derivatives are distinguished by their melting points (1H-nuclear magnetic resonance (1H-NMR), fourier transform infrared spectroscopy (FTIR)) spectra. Challenges that arise during GERD are minimized by using a better combination of drugs. It has a higher selectivity for the bladders muscarinic receptors. View and Download Full Article Rafid A. R. ALobaidy*, Nawal A. Rajab Furthermore, these findings point to the necessity for more research. The complexity of the current pharma market needs the most effective drug product development and production. One long-term complication is the ischemic heart disease (IHD) which is a major cause of morbidity and mortality. Skin allergy is a widespread skin problem at the level of different ages, and it occurs when an irritant comes into contact with the skin, and immune system believes it is under attack, so it overreacts and sends antibodies to help fight invaders. All authors have read and agreed to the published version of the manuscript. At the same time, P. expansum (D8), Cladosporium allicinum (J3) and Aspergillus sydowii (J11) were significantly superior to other isolates, with the highest laccase specific activity reaching 0.42, 0.32 and 0.26 unit/mg protein, respectively. In the current study, derivatives containing pyridine, 1,3,4-oxadiazole and 1,2,3-triazole heterocycles in their structures have been synthesized, 1,2,3-triazole moiety was synthesized using click chemistry, a powerful modular synthesis approach, and evaluated for in-vitro antifungal activity. Comparative Study of Liver Function Test in Cholelithiasis Patient Pre and Post Cholecystectomy 53. It causes a variety of symptoms, including urgency, incontinence, urine frequency, and nocturia. Roqaya A. Salih*, Zahraa H. M. Kadri, Hazima M. Al-Abassi Out of 19 patients undergoing cholecystectomy, pre-operative liver function tests (LFT) were normal in 11(61.11%) patients, and abnormal LFT was detected in 8 (44.44 %) patients. Hala Hussein*, Abdalnabi J. Abid, Zainab H. Alsaadi Ilaprazole, and tenatoprazole are currently under trial in humans and reported to have a longer duration of action.